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As ageneral rule, patients with PPA are younger (often 55–65years of age) than the characteristic age of onset for typi-cal AD (>65).

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Moreover, by decreasing fre-tive ventilation strategies to prevent lung injury. P-glycoprotein pump activityin the cells lining the bile canaliculi and luminal edgeof the proximal tubule promotes clearance throughdrug effl ux.
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